2025 ESMO | 精彩抢先看!结直肠癌领域中国研究一览
原创
2025-08-06
来源:快医精选
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一年一度的肿瘤领域盛会——2025年欧洲肿瘤内科学会年会(ESMO 2025)将于10月17日至21日在德国柏林隆重举行,届时将揭示众多前沿临床科研成果,并吸引全球知名专家教授进行研讨,共同促进临床肿瘤学的发展与进步。


目前,官网披露了本次大会的入选摘要标题,在结直肠癌的Poster和e-Poster领域,中国专家共有40项研究入选。医脉通特此整理如下,让我们先睹为快!


Poster session


1 摘要号:733P


研究名称(英文):Efficacy and safety of atezolizumab (Atezo) with or without tiragolumab (Tira) following neoadjuvant chemoradiotherapy (nCRT) in patients with locally advanced rectal cancer (NEOTERIC): a multicenter, randomized, open-label, parallel-group phase II study

讲者:许剑民 | 复旦大学附属中山医院


2 摘要号:739P


研究名称(英文):Deepath-MSI: A Clinic-Ready Deep Learning Model for Microsatellite Instability Detection in Colorectal Cancer Using Whole-Slide Imaging

讲者:Feng Xu  | 中国上海


3 摘要号:741P


研究名称(英文):Chemoradiotherapy (CRT) followed by sequential tislelizumab (TIS) + CAPOX and TIS for organ preservation in low rectal cancer (RELIEVE-01): primary results

讲者:汤文涛 | 复旦大学附属中山医院


4 摘要号:749P


研究名称(英文):A multicenter, randomized, phase II trial of short-course radiotherapy or long-course chemoradiation followed by mFOLFOXIRI consolidation chemotherapy for organ preservation in low rectal cancer

讲者:Kai Han | 中国广州


5 摘要号:750P


研究名称(英文):The Clinical Utility of Dynamic ctDNA in Predicting Response to Neoadjuvant Chemotherapy in Locally Advanced Rectal Cancer: A Post Hoc Analysis of the CONVERT Trial

讲者:Jing-Hua Tang | 中国广州


6 摘要号:753P


研究名称(英文):Global Burden of Colorectal Cancer from 1990 to 2021: Findings from the Global Burden of Disease Study 2021 and Projections to 2035

讲者:Liwei Fan | 中国北京


7 摘要号:756P


研究名称(英文):Machine Learning-Driven Integration of Gut Mucosal and Circulating Microbial Biomarkers for Superior Early Diagnosis of Colorectal Cancer

讲者:Ning Zhao | 中国西安


8 摘要号:762P


研究名称(英文):Confounders for incident colorectal cancer associated with smoking differ by sex

讲者:Hong-Hong Zhu | 中国衢州


9 摘要号:763P 


研究名称(英文):Clinical validation of the blood-based multiplex methylation assay, ColonAiQ, as a diagnostic aid for early detection of colorectal cancer

讲者:Xiaoyan Zhou | 中国上海


10 摘要号:765P


研究名称(英文):Interim analysis of Protector-C study:a prospective, multicenter cohort of utilizing circulating tumor DNA (ctDNA) methylation as postoperative surveillance for colorectal cancer (CRC)

讲者:王锡山 | 中国医学科学院肿瘤医院


11 摘要号:773P


研究名称(英文):Integration of Cadonilimab into Total Neoadjuvant Therapy for pMMR/MSS Locally Advanced Rectal Cancer: Phase II Efficacy and Safety Outcomes

讲者:Lingling Feng | 中国深圳


12 摘要号:778P


研究名称(英文):Prognostic Significance of Tumor Deposits in Locally Advanced Rectal Cancer: Post-hoc Analysis of a Phase III Trial

讲者:RunKai Cai | 中国广州


13 摘要号:779P


研究名称(英文):Preoperative Short-course Radiotherapy followed by Chemotherapy and PD-L1 inhibitor for Locally Advanced Rectal Cancer: a prospective phase II study

讲者:Ting Wang | 中国郑州


14 摘要号:783P


研究名称(英文):Neoadjuvant envafolimab combined with chemoradiotherapy in locally advanced rectal cancer: an exploratory, phase II study

讲者:Xu Guan | 中国北京


15 摘要号:784P


研究名称(英文):Extracellular volume fraction and standardized iodine concentration of dual-energy CT for prediction of metastatic lymph nodes in rectal cancer

讲者:Menghong Zou | 中国绵阳


16 摘要号:786P


研究名称(英文):Serplulimab Combined with CapeOX and Celecoxib as Neoadjuvant Therapy for Proficient Mismatch Repair Locally Advanced Mid-to-Low Rectal Cancer (SCAR)

讲者:丁克峰  | 浙江大学医学院附属第二医院


17 摘要号:796P


研究名称(英文):A phase II trial to evaluate the safety and efficacy of SSGJ-707, a bispecific antibody targeting PD-1 and VEGF, in combination with chemotherapy in patients with metastatic CRC

讲者:徐晓晶 | 上海交通大学医学院附属仁济医院


18 摘要号:797P


研究名称(英文):Irinotecan Liposome combined with 5-FU/LV and Bevacizumab as Second-Line Therapy for Metastatic Colorectal Cancer (IRIS): A Prospective, Multicenter, Single-Arm Phase II Study

讲者:Guingying Wang | 中国石家庄


19 摘要号:800P


研究名称(英文):A multicenter randomized phase II trial assessing the efficacy and safety mCapOX plus cetuximab with mFOLFOX6 plus cetuximab as first-line treatment for patients with RAS/BRAF wild-type metastatic colorectal cancer: Updated results of the CAPCET study

讲者:周裕文 | 四川大学华西医院


20 摘要号:806P


研究名称(英文):Efficacy and safety of JSKN003, a biparatopic anti-HER2 antibody conjugate (ADC), in patients with HER2-positive metastatic colorectal cancer (mCRC)

讲者:Dan Liu | 中国北京


21 摘要号:807P


研究名称(英文):Efficacy and Safety of HBM4003, an anti-CTLA-4 Antibody, Combined with Tislelizumab in MSS Metastatic Colorectal Cancer: A Multicenter, Phase II Study

讲者:张盼盼 | 北京大学肿瘤医院


22 摘要号:815P


研究名称(英文):Prospective Evaluation of Deepath-MSI for Microsatellite Instability Assessment in Colorectal Cancer: A Novel Whole Slide Image-Based Approach Versus Promega MSI Assay

讲者:Qian Wang | 中国上海


23 摘要号:819P


研究名称(英文):AI-based blood test results predict origins for cancers of unknown primary

讲者:Fei Tian | 中国天津


24 摘要号:820P


研究名称(英文):A Multicenter-Derived Nodal Classification System for Colon Cancer: Prognostic Significance of Metastatic Lymph Node Count and Anatomical Distribution

讲者:Zerong Cai | 中国广州


25 摘要号:831P


研究名称(英文):Cadonilimab Combined with FOLFOXIRI and Bevacizumab as First-Line Treatment for Microsatellite Stable/Proficient Mismatch Repair (MSS/pMMR) Metastatic Colorectal Cancer (mCRC): Update Result from a Multicenter, Phase II Study (SYLT-026)

讲者:林榕波 | 福建省肿瘤医院


26 摘要号:836P


研究名称(英文):Gut Microbiome and Metabolic Traits in Immunotherapy-Based Total Neoadjuvant Therapy for MSS Locally Advanced Rectal Cancer: A Longitudinal Cohort Study

讲者:Weiqing Lu | 中国上海


27 摘要号:842P


研究名称(英文):Combining lines of therapy algorithms and large language models to detect progression of metastatic colorectal cancer patients in electronic health records

讲者:Yi-hsin Yang | 中国台南


28 摘要号:845P


研究名称(英文):Liposomal irinotecan combined with capecitabine and bevacizumab as second-line therapy in metastatic colorectal cancer: A multi-center, single-arm study

讲者:Dan Su | 中国哈尔滨


29 摘要号:854P


研究名称(英文):Effect of immunonutrition on postoperative complications, nutrition and inflammatory status in patients with colorectal cancer: A prospective, observational study

讲者:周建平 | 中国医科大学附属第一医院


30 摘要号:860TiP


研究名称(英文):Neoadjuvant short-course radiotherapy (SCRT) plus iparomlimab and tuvonralimab (QL1706), CAPOX, and regorafenib in locally advanced rectal cancer (LARC): A randomized, multicenter, non-comparative phase 2 trial in progress

讲者:丁培荣 | 中山大学肿瘤防治中心


e-Poster session


1 摘要号:863eP


研究名称(英文):Impact of Inflammatory Status on Quality of Life in Patients with Advanced Colorectal Cancer: A Comprehensive Analysis

讲者:Xi Zhang | 中国北京


2 摘要号:866eP


研究名称(英文):A phase II, open-label study of toripalimab, cetuximab plus FOLFIRI as first-line treatment of unresectable left-sided RAS/BRAF wild-type metastatic colorectal cancer (Tesla study)

讲者:梁军 | 江苏省肿瘤医院


3 摘要号:874eP

 

研究名称(英文):First-line (1L) encorafenib + cetuximab + mFOLFOX6 in patients with BRAF V600E-mutant metastatic colorectal cancer (mCRC) in China: results from the phase 3 BREAKWATER study

讲者:Xicheng Wang | 中国广州


4 摘要号:881eP


研究名称(英文):Long-term neoadjuvant chemoradiotherapy (nCRT) combined with camrelizumab for locally advanced rectal cancer: a single-arm, prospective, phase II clinical study

讲者:Chung B. Zhao | 中国哈尔滨


5 摘要号:894eP


研究名称(英文):Global Disease Burden of Colorectal Cancer Attributable to High BMI Has More Than Doubled Over the Past 30 Years

讲者:Wenjie W. Li | 中国佛山


6 摘要号:898eP


研究名称(英文):Fruquintinib alternating with bevacizumab plus capecitabine as maintenance therapy after first-line treatment in metastatic colorectal cancer (mCRC): A multicenter, open-label, Phase II Study

讲者:廖旺军 | 南方医科大学南方医院


7 摘要号:905eTiP


研究名称(英文):TORCH-iTNT: A randomized phase II trial of CAPOX plus PD-1 inhibitor with or without short-course radiotherapy for proficient mismatch repair locally advanced rectal cance

讲者:王雅琪 | 复旦大学附属肿瘤医院


8 摘要号:907eTiP


研究名称(英文):FTM-JSNO-03:A phase II study of fecal microbiota transplantation (FMT) plus QL1706 plus Bevacizumab plus XELOX for first-line (1L) treatment of advanced Microsatellite-stable (MSS) type colon cancer with liver metastasis

讲者:Hanjue Dai | 中国常州


9 摘要号:911eTiP


研究名称(英文):Node-sparing modified Short-Course Radiation Combined With CAPOX and Sintilimab for MSS Locally Advanced Colon Cancer : A randomized, prospective, multicenter, open-label clinical trial (mRCAT-C)

讲者:劳伟峰 | 浙江大学医学院附属邵逸夫医院


10 摘要号:912eTiP


研究名称(英文):SCRT + mFOLFOX6 + PD-1 Antibody + Targeted Therapy for HIgh-Risk pMMR/MSS Rectal Cancer (CRIT)

讲者:Fang He | 中国广州

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